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Vitamin-B12

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Vitamin B12, also known as cobalamin, is an essential water-soluble vitamin that plays a crucial role in various bodily functions. Here are some key points about Vitamin B12:

Benefits
1. Red Blood Cell Formation: Vitamin B12 is vital for the production of healthy red blood cells, which help transport oxygen throughout the body. A deficiency can lead to anemia.
2. DNA Synthesis: It is essential for DNA synthesis, which is necessary for cell division and growth.
3. Nervous System Health: Vitamin B12 helps maintain the health of nerve cells and supports proper neurological function.
4. Energy Production: It is involved in the metabolism of every cell in the body, particularly affecting DNA synthesis and energy production.
5. Mood and Brain Health: Adequate levels of Vitamin B12 are associated with improved mood and cognitive function. It helps produce neurotransmitters that affect mood regulation.

Sources
Vitamin B12 is naturally found in animal products. Some of the best sources include:
- Meat: Beef, pork, lamb, and poultry.
- Fish and Seafood: Salmon, tuna, trout, clams, and other shellfish.
- Dairy Products: Milk, cheese, and yogurt.
- Eggs: Particularly the yolks.
- Fortified Foods: Some plant-based milk, breakfast cereals, and nutritional yeast are fortified with Vitamin B12.
- Supplements: Available in various forms, including tablets, capsules, and injections, and are particularly important for vegetarians and vegans who might not get enough from diet alone.

Recommended Daily Intake
The recommended daily intake of Vitamin B12 varies by age, sex, and life stage:
- Infants (0-6 months): 0.4 mcg
- Infants (7-12 months): 0.5 mcg
- Children (1-3 years): 0.9 mcg
- Children (4-8 years): 1.2 mcg
- Children (9-13 years): 1.8 mcg
- Adults (14+ years): 2.4 mcg
- Pregnant Women: 2.6 mcg
- Breastfeeding Women: 2.8 mcg

Deficiency
A deficiency in Vitamin B12 can lead to several health issues, including:
- **Megaloblastic Anemia**: Characterized by large, immature red blood cells that do not function properly.
- **Neurological Symptoms**: Such as numbness and tingling in the hands and feet, difficulty walking, memory loss, and mood changes.
- Fatigue and Weakness: Due to the reduced ability of red blood cells to carry oxygen.
- Glossitis and Mouth Ulcers: Inflammation of the tongue and sores in the mouth.

At-Risk Groups
Certain groups are at higher risk of Vitamin B12 deficiency, including:
- Vegetarians and Vegans: Since B12 is primarily found in animal products.
- Older Adults: Due to decreased absorption efficiency.
- People with Gastrointestinal Disorders: Such as Crohn's disease or celiac disease, which can affect nutrient absorption.
- Individuals Taking Certain Medications: Such as metformin or proton pump inhibitors, which can interfere with B12 absorption.

 

 

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What is Vitamin B12?

 

 

 

 

Vitamin B12, also known as cobalamin, is a water-soluble vitamin that plays a crucial role in various bodily functions, including nerve function, red blood cell production, and DNA synthesis.

 

Why is Vitamin B12 important?

Vitamin B12 is essential for maintaining healthy nerve cells, synthesizing DNA, and producing red blood cells that carry oxygen throughout the body. It also supports energy metabolism and helps prevent a type of anemia called megaloblastic anemia.

What are the sources of Vitamin B12?

meat, fish, dairy products, and eggs. Some fortified cereals and plant-based milk alternatives may also contain Vitamin B12, but it is generally less bioavailable than in animal sources.

Who is at risk of Vitamin B12 deficiency?

Vegans, vegetarians, older adults, and individuals with certain medical conditions that affect nutrient absorption (such as pernicious anemia or gastrointestinal disorders) are at higher risk of Vitamin B12 deficiency. Additionally, long-term use of certain medications like proton pump inhibitors (PPIs) or metformin can also interfere with B12 absorption.

What are the symptoms of Vitamin B12 deficiency?

Symptoms of Vitamin B12 deficiency may include fatigue, weakness, numbness or tingling in the hands and feet, difficulty walking, memory problems, and mood changes. Severe deficiency can lead to nerve damage and irreversible neurological problems if left untreated.

How is Vitamin B12 deficiency treated?

Vitamin B12 deficiency is typically treated with Vitamin B12 supplements, either in oral form or through injections, depending on the severity of the deficiency and the underlying cause. In cases of pernicious anemia or severe malabsorption, lifelong supplementation may be necessary.

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